41
Charles Palmer: Nasal oral respiratory interface. The Penn State Research Foundation, McKee Voorhees & Sease, May 13, 2003: US06561192 (53 worldwide citation)


The present invention provides an apparatus and a method for stabilizing at least one medical device such as a tracheal or gastric tube entering or covering at least one facial cavity such as the mouth and/or nose, taking advantage of a stabilization stent to secure to a patient's face the trac ...


42
Mcbride Mark W, Boger David A, Campbell Robert L, Dillon Gregory P, Hambric Stephen A, Kunz Robert F, Leschinsky Boris, Mallison Thomas M, Runt James P, Walsh Justin M: Heart assist device with expandable impeller pump. The Penn State Research Foundation, Datascope Investment, Mcbride Mark W, Boger David A, Campbell Robert L, Dillon Gregory P, Hambric Stephen A, Kunz Robert F, Leschinsky Boris, Mallison Thomas M, Runt James P, Walsh Justin M, COHEN Robert B, October 4, 2007: WO/2007/112033 (53 worldwide citation)


An impeller includes a hub and at least one blade supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub. The impeller may be part of a pump ...


43
Gary S Settles: Supersonic abrasive iceblasting apparatus. The Penn State Research Foundation, Thomas J Monahan, July 28, 1998: US05785581 (52 worldwide citation)


The specification discloses an apparatus and method for forming and projecting a continuous flow of frozen particles for the purpose of abrasive cleaning of substrate surfaces. The device utilizes a cryogenic fluid/dry air mixture that interacts with atomized water to form ice crystals. The crystals ...


44
House Kurt Z, House Christopher H, Aziz Michael J, Schrag Daniel Paul: Carbon dioxide capture and related processes. President And Fellows Of Harvard College, The Penn State Research Foundation, House Kurt Z, House Christopher H, Aziz Michael J, Schrag Daniel Paul, WALAT Robert H, February 14, 2008: WO/2008/018928 (52 worldwide citation)


Processes for capturing carbon dioxide are described. The carbon dioxide may be captured from the atmosphere and/or from the waste stream of a carbon dioxide point source (e.g., power plants, chemical plants, natural gas fields, oil fields, industrial sites, etc.). The processes can involve capturin ...


45
Stephen J Benkovic, Frank Salinas: Methods for nucleic acid manipulation. The Penn State Research Foundation, Welsh & Katz, August 16, 2005: US06929915 (50 worldwide citation)


A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is tre ...


46
Jia Li, James Z Wang: Real-time computerized annotation of pictures. The Penn State Research Foundation, Gifford Krass Sprinkle Anderson & Citkowski P C, Douglas L Wathen, May 10, 2011: US07941009 (49 worldwide citation)


A computerized annotation method achieves real-time operation and better optimization properties while preserving the architectural advantages of the generative modeling approach. A novel clustering algorithm for objects is represented by discrete distributions, or bags of weighted vectors, thereby ...


47
Ali Kaan Kalkan, Stephen J Fonash: Electronic and opto-electronic devices fabricated from nanostructured high surface to volume ratio thin films. The Penn State Research Foundation, Perkins Smith & Cohen, Peter J Borghetti, John A Hamilton, July 19, 2005: US06919119 (48 worldwide citation)


An electronic or opto-electronic device or a chemical sensor comprising: an interpenetrating network of a nanostructured high surface area to volume ratio film material and an organic/inorganic material forming a nanocomposite. The high surface area to volume film material is obtained onto an electr ...


48
Thomas N Jackson, Hagen Klauk: Organic light emitters with improved carrier injection. The Penn State Research Foundation, Ohlandt Greeley Ruggiero & Perle, April 13, 2004: US06720572 (48 worldwide citation)


A light emitting device with improved carrier injection. The device has a layer of organic light emitting material and a layer of organic semiconductor material that are interposed between first and second contact layers. A carrier transport layer,may optionally be included between the semiconductor ...


49
Harry R Allcock, Alexander K Andrianov, Robert S Langer, Karyn B Visscher: Phosphazene polyelectrolytes as immunoadjuvants. Massachusetts Institute of Technology, Virus Research Institute, The Penn State Research Foundation, Arnall Golden & Gregory, October 8, 1996: US05562909 (45 worldwide citation)


A immunoadjuvant soluble phosphazene polyelectrolyte is disclosed. In one embodiment, the polymeric adjuvant is an poly(organophosphazene) with (i) ionized or ionizable pendant groups that contain, for example, carboxylic acid, sulfonic acid, or hydroxyl moieties, and (ii) pendant groups that are su ...


50
C Frank Bennett, Allan Lipton, Lois M Witters: Oligonucleotide inhibition of epidermal growth factor receptor expression. Isis Pharmaceuticals, The Penn State Research Foundation, Woodcock Washburn Kurtz Mackiewicz & Norris, June 22, 1999: US05914269 (45 worldwide citation)


Compounds, compositions and methods are provided for inhibiting the expression of human EGFR. The compositions comprise oligonucleotides complementary to mRNA targeted to nucleic acids encoding EGFR. Methods of using these oligonucleotides for inhibition of EGFR expression and for treatment of disea ...



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