1
Gao Guangping, Wilson James M, Alvira Maricio: (avv) Sequences and a kit for the method. Trustees Of The University Of, May 14, 2003: EP1310571-A2 (95 worldwide citation)


A method for dctecting and isolating AAV sequences in a sample of DNA obtained from tissue or cells is provided. The invention further provides AAV sequences identified by this method, and vectors constructed using these sequences.


2
Wilson James M, Gao Guangping, Alvira Mauricio R, Vandenberghe Luc H: (aav) Clades, sequences, vectors containing same, and uses therefor. The Trustees Of The University Of Pennsylvania, Wilson James M, Gao Guangping, Alvira Mauricio R, Vandenberghe Luc H, KODROFF Cathy A, April 14, 2005: WO/2005/033321 (24 worldwide citation)


Sequences of adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the inventi ...


3
Gao Guangping, Shen Guobin, Li Shipeng: Accelerating video encoding using graphics processor unit. Microsoft, April 6, 2006: JP2006-094494 (16 worldwide citation)


PROBLEM TO BE SOLVED: To accelerate a video encoding without rasing a speed of a CPU.SOLUTION: A present frame of a video signal is decided and a motion estimating data related to the present frame is decided using a processor unit. Then, the video signal is encoded to a digital video data using the ...


4
GAO GUANGPING: Novel aav s and uses thereof. UNIVERSITY OF MASSACHUSETTS, Lockhart Helen C, December 2, 2010: WO/2010/138263 (13 worldwide citation)


The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid pr ...


5
Vandenberghe Luk, Gao Guangping, Wilson James M: Method of increasing the function of an aav vector. The Trustees Of The University Of Pennsylvania, Vandenberghe Luk, Gao Guangping, Wilson James M, KODROFF Cathy A, October 19, 2006: WO/2006/110689 (9 worldwide citation)


A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton ...


6
Gao Guangping, Shen Guobin, Li Shipeng: Accelerated video encoding using a graphics processing unit. Microsoft, March 29, 2006: EP1641278-A2 (8 worldwide citation)


The systems and methods described herein are directed at accelerating video encoding using a graphics processing unit. In one aspect, a video encoding system uses both a central processing unit (CPU) and a graphics processing unit (GPU) to perform video encoding. The system implements a technique th ...


7
Gao Guangping, Wilson James M, Alvira Mauricio R: Method for direct rescue and amplification of integrated viruses from cellular dna of tissues. Trustees Of The University Of, November 5, 2003: EP1359217-A1 (5 worldwide citation)


A method for isolating AAV viruses from cellular DNA of mammalian tissues comprises transfecting the digested DNA into cells, rescuing the virus and amplifying it through serial passages in the presence of adenovirus helper functions. Kits useful for performing this method are also provided.


8
Wilson James M, Gao Guangping, Roy Soumitra: Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use. Trustees Of The University Of, July 16, 2008: EP1944043-A1 (4 worldwide citation)


A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.


9
GAO Guangping, ZHANG Gongwei, WANG Hongyan, XU Zuoshang: Vecteurs aav ciblant le système nerveux central et leurs procédés dutilisation, Cns targeting aav vectors and methods of use thereof. University Of Massachusetts, GAO Guangping, ZHANG Gongwei, WANG Hongyan, XU Zuoshang, YOUNG Daniel W, October 27, 2011: WO/2011/133890 (3 worldwide citation)


The invention in some aspects relates to recombinant adeno-associated viruses useful for targeting transgenes to CNS tissue, and compositions comprising the same, and methods of use thereof. In some aspects, the invention provides methods and compositions for treating CNS-related disorders.


10
GAO GUANGPING, WILSON JAMES M, VANDENBERGHE LUK, ALVIRA MAURICIO R: Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof, Adenoassoziierte Virus-Claden, Sequenzen, diese enthaltende Vektoren und ihre Verwendungen, Variantes des virus associés aux adénovirus (AAV), séquences, vecteurs les contenant et leur utilisation. UNIV PENNSYLVANIA, July 20, 2011: EP2345731-A1 (2 worldwide citation)


Sequences of adeno-associated virus capsids and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles. AAV-mediated delivery of therapeutic and immunogenic genes using the vectors of the inventi ...



Click the thumbnails below to visualize the patent trend.