1
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Abdell Aziz Ben Jebria, Robert S Langer: Aerodynamically light particles for pulmonary drug delivery. Massachusetts Institute of Technology, The Penn State Research Foundation, Arnall Golden & Gregory, February 23, 1999: US05874064 (248 worldwide citation)


Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of a biodegradable material and have a tap density less than 0.4 g/cm.sup.3 and ...


2
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Abdell Aziz Ben Jebria, Robert S Langer: Aerodynamically light particles for pulmonary drug delivery. Massachusetts Institute of Technology, Penn State Research Foundation, Hamilton Brook Smith & Reynolds P C, October 24, 2000: US06136295 (153 worldwide citation)


Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of a biodegradable material and have a tap density less than 0.4 g/cm.sup.3 and ...


3
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Robert S Langer, Abdellaziz Ben Jebria: Porous particles for deep lung delivery. The Penn Research Foundation, Hamilton Brook Smith & Reynolds P C, July 3, 2001: US06254854 (92 worldwide citation)


Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm


4
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Robert S Langer, Abdellaziz Ben Jebria: Porous particles for deep lung delivery. The Penn Research Foundation, Massachusetts Institute of Technology, Hamilton Brook Smith & Reynolds P C, September 10, 2002: US06447753 (69 worldwide citation)


Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm


5
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Abdellaziz Ben Jebria, Robert S Langer: Aerodynamically light particles for pulmonary drug delivery. October 21, 2003: US06635283 (63 worldwide citation)


Improved aerodynamically light particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the aerodynamically light particles are made of biodegradable material and have a tap density of less than 0.4 g/cm


6
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Robert S Langer, Abdellaziz Ben Jebria: Porous particles comprising excipients for deep lung delivery. The Penn Research Foundation, Massachesetts Institute of Technology, Hamilton Brook Smith & Reynolds P C, August 20, 2002: US06436443 (35 worldwide citation)


Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm


7
Giovanni Caponetti, Pier Luigi Catellani, Ruggero Bettini, Paolo Colombo, Paolo Ventura: Powder particles with smooth surface for use in inhalation therapy. Chiesi Farmaceutici S p A, Oblon Spivak McClelland Maier & Neustadt P C, July 15, 2008: US07399528 (24 worldwide citation)


Carrier particles, for use in the preparation of powdery mixtures for administration by inhalation, and having a median diameter of greater than 90 microns and a surface rugosity expressed as the fractal dimension of less than or equal to 1.1, may be prepared by subjecting particles having a median ...


8
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Robert S Langer, Abdellaziz Ben Jebria: Amorphous porous particles for deep lung delivery. The Penn State Research Foundation, Massachusetts Institute of Technology, Hamilton Brook Smith & Reynolds P C, September 10, 2002: US06447752 (15 worldwide citation)


Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm


9
Michael W Lipp, Richard P Batycky, Giovanni Caponetti: Formulation for spray-drying large porous particles. Advanced Inhalation Research, Carolyn S Elmore, Anne I Craig, Elmore Craig P C, June 15, 2004: US06749835 (13 worldwide citation)


Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a solvent such as an aqueous-organic solvent. The colloidal solution can also include a therapeutic, prophyla ...


10
David A Edwards, Giovanni Caponetti, Jeffrey S Hrkach, Noah Lotan, Justin Hanes, Robert S Langer, Abdellaziz Ben Jebria: Porous particles comprising excipients for deep lung delivery. Massachusetts Institute of Technology, The Penn State Research Foundation, Carolyn S Elmore, Anne I Craig, Elmore Craig P C, May 25, 2004: US06740310 (13 worldwide citation)


Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm



Click the thumbnails below to visualize the patent trend.