1
Tae G Park, Smadar Cohen, Robert S Langer: Controlled drug delivery using polymer/pluronic blends. Massachusetts Institute of Technology, Kilpatrick & Cody, July 19, 1994: US05330768 (334 worldwide citation)


A new series of degradable polymeric matrices were prepared by blending polymers that degrade by hydrolysis such as poly(L-lactic acid)(PLA), and nonionic Pluronic.TM. surfactants, block copolymers of polyethyleneoxide (PEO) and polypropyleneoxide (PPO). The water content of the polymer blend films ...


2
Smadar Cohen, Carmen Bano, Karyn B Visscher, Marie Chow, Harry R Allcock, Robert S Langer: Ionically cross-linked polymeric microcapsules. Massachusetts Institute of Technology, Pennsylvania Research Corporation, Kilpatrick & Cody, September 22, 1992: US05149543 (169 worldwide citation)


A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked wi ...


3
Smadar Cohen, Alexander K Andrianov, Margaret Wheatley, Harry R Allcock, Robert S Langer: Gas-filled polymeric microbubbles for ultrasound imaging. Massachusetts Institute of Technology, The Penn State Research Foundation, Arnall Golden & Gregory, January 30, 1996: US05487390 (132 worldwide citation)


Compositions, methods for preparing and methods of using air-filled polymeric microcapsules for ultrasound imaging are disclosed. Air-encapsulating microcapsules are formed by ionotropically gelling synthetic polyelectrolytes such as poly(carboxylatophenoxy)phosphazene, poly(acrylic acid), poly(meth ...


4
Smadar Cohen, Carmen Bano, Karyn B Visscher, Marie Chow, Harry R Allcock, Robert S Langer: Ionically cross-linked polymeric microcapsules. Massachusetts Institute of Technology, The Penn State Research Foundation, Arnall Golden & Gregory, February 27, 1996: US05494682 (54 worldwide citation)


A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked wi ...


5
Lilia Shapiro, Rachel Glicklis, Smadar Cohen: Method of forming polysaccharide sponges for cell culture and transplantation. Ben Gurion University of the Negev, Merchant & Gould P C, January 1, 2002: US06334968 (51 worldwide citation)


A polysaccharide sponge characterized by having: (i) an average pore size in the range between about 10 &mgr;m to about 300 &mgr;m; (ii) an average distance between the pores being the wall thickness of the pores in the range between about 5 &mgr;m to about 270 &mgr;m; and (iii) an E-modulus of elas ...


6
Smadar Cohen, Carmen Bano, Karyn B Visscher, Marie B Chow, Harry R Allcock, Robert S Langer: Ionically cross-linked polymeric microcapsules. May 3, 1994: US05308701 (46 worldwide citation)


A method for encapsulating biologically-labile materials such as proteins, liposomes, bacteria and eucaryotic cells within a synthetic polymeric capsule, and the product thereof, are disclosed. The method is based on the use of a water-soluble polymer with charged side chains that are crosslinked wi ...


7
Smadar Cohen, Alexander K Andrianov, Margaret Wheatley, Harry R Allcock, Robert S Langer: Polymeric microparticles containing agents for imaging. Massachusetts Institute of Technology, The Penn State Research Foundation, Arnall Golden & Gregory, October 8, 1996: US05562099 (41 worldwide citation)


Compositions, methods for preparing and methods of using contrast agent-filled polymeric microparticles for imaging are disclosed. In a preferred embodiment, air-encapsulating microparticles are formed by ionotropically gelling synthetic polyelectrolytes such as poly(carboxylatophenoxy)phosphazene, ...


8
Smadar Cohen, Esther Lobel: Ophthalmic delivery system. Teva Pharmaceutical, The Ben Gurion University of the Negev, Kenyon & Kenyon, July 7, 1998: US05776445 (36 worldwide citation)


The present invention relates to formulations particularly well suited for use as delivery systems in the delivery of an active agent to the eye. The formulations comprise an alginate having a particular proportion of guluronic acid.


9
Smadar Cohen, Jonathan Leor: Injectable cross-linked polymeric preparations and uses thereof. Ben Gurion University of the Negev Research and Development Authority, Servilla Whitney, June 11, 2013: US08461132 (34 worldwide citation)


A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature for at least 24 hours; and (ii) assuming a gel state following deposition within the body tissue. The ...


10
Lilia Shapiro, Rachel Glicklis, Smadar Cohen: Polysaccharide sponges for cell culture and transplantation. Ben Gurion University of the Negev, Merchant & Gould P C, July 30, 2002: US06425918 (30 worldwide citation)


A polysaccharide sponge characterized by having: (i) an average pore size in the range between about 10 &mgr;m to about 300 &mgr;m; (ii) an average distance between the pores being the wall thickness of the pores in the range between about 5 &mgr;m to about 270 &mgr;m; and (iii) an E-modulus of elas ...



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